The creation of synthetic life from scratch: Future reality or unattainable possibility?

Autores/as

  • José María Gómez Gómez OAS-BiosAstronomy Group

Resumen

The origin of Life is one of the fundamental mysteries still unsolved by the modern science. The actual dominant orthodox scientific paradigm in Biological Sciences has as fundamental tenets that Life is a natural phenomenon as well as that the origin of Life would be an understandable event. Life apparently does not require of supplementary «vital principles» transcendent to the physical-chemical laws («materialistic forces») that govern non-living phenomena. No supernatural causes are required to explain Life. Here I have called this vision the mechanistic vital-less paradigm of Life. On the contrary the Vitalism is an old and discredited doctrine, which sustains that Life is a singular phenomenon that requires of the action of «vital forces» exclusives to living domain. The recent creation of a bacterial chromosome by Craig Venter’s team and the successful transfer of it into a bacterium, where the native DNA has been replaced, has created the expectation of the creation of synthetic Life (SLife-Lab) from scratch could be a reality in the next years. However, despite this scientific notable milestone, the dream of the creation of autonomous SLab-Life (the so-called a second origin) has not been realized yet. Thus, in my opinion, an open question that still remains is this: Why it has not been SLab-Life created yet? Another question related to the previous is: Is Vitalism an idea completely dead? Here, I discuss these issues taking account a historical perspective

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Biografía del autor/a

José María Gómez Gómez, OAS-BiosAstronomy Group

Observatorio Astronómico de Segurilla (OAS)

Citas

F. JACOB, The Logic of Life, A History of Heredity, Princeton University Press, Princeton, 1993.

SCHRÖDINGER, E., What is Life, Cambridge University Press, Cambridge, 1944.

TIRARD, S.; MORANGE, M., and LAZCANO, A., «The definition of Life: A brief history of an elusive scientific endeavor», Astrobiology 10: 1003-1009 (2010).

CLELAND, C. E., and CHYBA, C. F., «Defining life», Orig Life Evol Biosph 32: 387-393 (2002).

BENNER, S. A., «Defining life», Astrobiology 10: 1021-1030 (2010).

GÓMEZ-GÓMEZ, J. M., «Aging in Bacteria, Inmortality or not- A critical review», Curr Aging Sci 3: 198-218 (2010).

KOSHLAND, D. E., «The seven pillars of life», Science 295: 2215-2216 (2002).

YOCKEY, H. P., Information Theory, Evolution, and the Origin of Life, Cambridge University Press, 2005.

NELSON, D. L., and COX, M. M., Principles of Biochemistry, Lehninger, Fourth Edition, Freeman Company, 2004.

MCKAY, C. P., «What is life – and how do we search for it in other worlds?». Plos Biology e302. doi:10.1371/journal.pbio.0020302 (2004).

CRICK, F., «Central dogma of molecular biology», Nature 227: 561-563 (1970).

SERVICE, R. F., «Researchers create first autonomous synthetic Life form», Science 299: 640 (2003).

WATSON, J.; BAKER, T. A.; BELL, S. P.; GANN, A.; LEVINE, M., and LOSICK, R., Molecular Biology of the Gene, Sixth Edition, Cold Spring Habor Laboratory Press, New York, 2008.

ALBERTS, B.; BRAY, D.; LEWIS, J.; RAFF, M.; ROBERTS, K., and WATSON, J. D., Molecular Biology of the Cell, 3rd edition, Garland Publishing Inc., 1994.

BRAY, D., Wetware: A Computer in Every Living Cell, Yale University Press, 2009.

HAYNIE, D. T., Biological Thermodinamics, Cambridge University Press, 2001.

KURZYNSKI, M., The Thermodynamics Machinery of Life, Springer-Verlarg, 2006.

RIDLEY, M., Evolution, Oxford University Press, 2004.

DARWIN, R. C., On the Origin of Species by Means of Natural Selection or, the Preservation of Races in the Struggle for Life, London, John Murray, 1859.

KIRSCHNER, M., and GERHART, J., «Evolvability», Proc Natl Acad Sci USA 95: 8420-8427 (1998).

LAUGHLIN, G. A., «Dance of Extrasolar Planets», Science 330: 47-48 (2010). The Extrasolar Planets Encyclopaedia: http://exoplanet.eu/index.php

Mission Kepler: http://kepler.nasa.gov/

GILMOUR, I., and SEPHTON, M. A. (eds.), An Introduction to Astrobiology, Cambridge University Press, 2003.

BLUMBERG, B. S., «Discovery Astrobiology, space and the future age of discovery», Phil. Trans. R. Soc. A 369: 508-515 (2011).

DE DUVE, C., Vital Dust: Life as a Cosmic, Imperative, Basic Books, New York, 1995.

BRUNO, G., Sobre el infinito y el mundo, Editorial Orbis, Barcelona, 1984.

MAYR, E., The Growth of Biological Thought: Diversity, Evolution, and Inheritance, Belknap, Cambridge, MA, 1982.

FARLEY, J., The Spontaneous Generation Controversy from Descartes to Oparin, Baltimore: The Johns Hopkins University Press, 1977.

GRAEME, H. K., Vital Forces, The discovery of molecular basis of Life, Academic Press, 2000.

HARRIS, H., The Birth of the Cell, Yale University Press, 1999.

YOUNG, D., The Discovery of Evolution, 2nd edition, Cambridge University Press, 2011.

WOESE, C., «The Universal Ancestor», Proc Natl Acad Sci USA 95: 6854-6859 (1998).

ZIMMER, C., Evolution. The Triumf of a Idea, WGBH Educational Foundation, 2001.

WATSON, J., «DNA», The Secret of Life, Arrow Books, 2004.

KAY, L., Who Wrote the Book of Life? A History of the Genetic Code (Writing Science), Stanford University Press, 2000.

ALON, U., An introduction to systems biology design principles of biological circuits, Chapman & Hall/CRC, 2007.

GIBSON, D. G., GLASS, J. I., LARTIGUE, C., NOSKOV, V. N., CHUANG, R. Y., ALGIRE, M. A., BENDERS, G. A., MONTAGUE, M. G., MA, L., and MOODIE, M. M., et al., «Creation of a bacterial cell controlled by a chemically synthesized genome», Science 329: 52-56 (2010).

LAHAV, N., Biogenesis: Theories of Life’s Origin, Oxford University Press, 1999.

ZIMMER, C., «On the origin of Life on Earth», Science 323: 198-199 (2009).

FRY, I., The Emergence of Life on Earth: A Historical and Scientific Overview, Rutgers University Press (New Brunswick, NJ, USA), 2000.

OPARIN, A. I., Life: Its Nature, Origin and Development, Academic Press, 1961.

HALDANE, J. B. S., «The origin of life», Rationalist Annual 148: 3-10 (1929).

MILLER, S. L., «A production of amino acids under possible primitive Earth conditions», Science 117: 528-529 (1953).

BADA, J. L., and LAZCANO, A., «Some like it hot, but not the first biomolecules», Science 296: 1982-1983 (2002).

MARTIN, W., BAROSS, J., KELLEY, D., and RUSSELL, M. J., «Hydrothermal vents and the origin of life», Nature Rev Microbiol 6: 805-814 (2008).

KOONIN, E. V., SENKEVICH, T. G., and DOLJA, V. V., «The ancient virus world and evolution of cells», Biol Direct 1:29 doi:10.1186/1745-6150-1-29 (2006).

ORGEL, L. E., «Prebiotic chemistry and the origin of the RNA world», Crit. Rev. Biochem. Mol. Biol. 39: 99-123 (2004).

CHEN, I. A., «The Emergence of cells during the origin of Life», Science 314: 1558-1559 (2006).

SMITH, J. M., and SZATHMÁRY, E., The Major Transitions in Evolution, Oxford University Press, 1995.

WÄCHTERSHÄUSER, G., «Life as we don’t know it», Science: 1307-1308 (2000).

WOESE, C. R., «On the evolution of cells», Proc Natl Acad Sci USA 99: 8742-8747 (2002).

LEWIN, R., Complexity: Life at the Edge of Chaos, New York: Macmillan Publishing Co., 1992.

HOLLAND, J. H., Emergence: From Chaos to Order, Helix Books, 1998.

ANDERSON, P. W., «More is different», Science 177: 393-396 (1972).

ARRHENIUS, S., Worlds in the Making: The Evolution of the Universe, New York, Harper & Row, 1908.

THOMAS, P. J., HICKS, R. D., CHYBA, C. F., and MCKAY, C. P., Comets and the Origin and Evolution of Life, Springer, 2006.

ARRHENIUS, S., Worlds in the Making: The Evolution of the Universe, New York, Harper & Row, 1908.

GONZÁLEZ-TORIL, E.; MARTÍNEZ-FRÍAS, J.; GÓMEZ-GÓMEZ, J. M.; RULL, F., and AMILS, R., «Iron meteorites can support the growth of acidophilic chemolithoautotrophic microorganisms», Astrobiology 5: 406-414 (2005).

CRICK, F., Life, Its Origin and Nature, Simon and Schuster, 1981.

WICKRAMASINGHE, C., «The astrobiological case for our cosmic ancestry», Inter J Astrobiol 9: 119-129 (2010).

LUISI, P. L., The Emergence of Life: From Chemical Origins to Synthetic Biology, Cambridge University Press, 2006.

TREVORSA, J. T., and ABE, D. L., «Chance and necessity do not explain the origin of life», Cell Biology International 28: 729-739 (2004).

SCHOPF, J.W., In the Cradle of Life: The Discovery of the Earth’s Earliest Fossils, Princeton Univ. Press, Princeton, 1999.

BERGSON, H. L., L’évolution créatrice, Presses Universitaires Paris, 1946.

PENNISI, E., «Synthetic genome brings new Life to bacterium», Science 328: 958-959 (2010).

SEVERAL AUTHORS, «Scientifc Opinions. Life after the synthetic cell», Nature 465: 422-424 (2010).

INGO, M., A History of Thermodynamics: the Doctrine of Energy and Entropy, Springer-Verlarg, 2007.

COHAN, F. M., «Synthetic Biology: Now that we’re creators, what should we create», Curr Biol, R675-R677 (2010).

KAISER, J., «Oversight but no strict rules for synthetic biology», Science 330: 1166 (2010).

GOODSELL, D. S., The Machinery of Life, Springer Science, 2006.

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Cómo citar

Gómez Gómez, J. M. (2013). The creation of synthetic life from scratch: Future reality or unattainable possibility?. Pensamiento. Revista De Investigación E Información Filosófica, 67(254 S.Esp), 831–841. Recuperado a partir de https://revistas.comillas.edu/index.php/pensamiento/article/view/1567